The Ultimate Guide To LDN-27219 as a cancer drug candidate
A person significantly interesting compound is LDN-27219. Though most tTG inhibitors are intended to bind for the protein crosslinking active web page, LDN-27219 as a substitute binds on the nucleotide binding pocket of the enzyme although it's in its shut-point out conformation, and stabilizes that conformation to forestall crosslinking activity.7